Anne yaşı dağılımının gebelikle ilişkili komplikasyonlar ve neonatal sonuçlar üzerindeki etkisi: tek merkezli retrospektif bir deneyim
Abstract
Amaç: İleri yaş gebeliklerde anne ve bebek için olası riskleri belirlemektir.
Gereç ve Yöntem: Bu çalışma, 2020-2023 yılları arasında 24 ila 42 haftalar arasında canlı doğum yapmış 14192 vakayı inceleyen retrospektif bir arşiv taramasıdır.
Bulgular: İleri yaş gebelerde preeklampsi, gestasyonel hipertansiyon, gestasyonel diabetes mellitus, membran rüptürü ve olası düşük sıklığı diğer gruplara göre yüksekti. Neonatal sonuçlara göre gruplar karşılaştırıldığında Adölesan yaşta düşük doğum ağırlığı sıklığı ileri yaş gebelere göre daha yüksekti. Makrozomi açısından gruplar karşılaştırıldığında makrozomi sıklığı ileri yaş grubunda diğer gruplara göre daha yüksekti.
Sonuç: İleri yaştaki gebeliklerin hem anne hem de bebek için daha komplike olabileceği bilinmeli ve gebelik takipleri daha dikkatli yapılmalıdır.
Keywords
İleri yaş gebelik Adölesan gebelik Gebelik komplikasyonları Erken membran rüptürü Neonatal sonuçlar
Ethical Statement
The study received non-interventional ethics committee approval from the Ethics Committee of Van Regional Training and Research Hospital. The approval number is 2023/01-05. The study was managed in accordance with the principles of the Declaration of Helsinki.
Supporting Institution
No person/organization is supporting this study financially.
References
- Osterman M, Hamilton B, Martin JA, Driscoll AK, Valenzuela CP. Births: Final Data for 2020. Natl Vital Stat Rep. 2021;70(17):1-50.
- World Health Organization. United Nations Department of Economic and Social Affairs. World Population Prospects: 2019 Revision. Geneva, Switzerland: World Health Organization; 2019.
- General Directorate of Civil Registration and Nationality. TurkStat, Birth Statistics, 2014.
- Meh C, Thind A, Ryan B, Terry A. Levels and determinants of maternal mortality in northern and southern Nigeria. BMC Pregnancy Childbirth. 2019;19(1):417.
- Kumari U, Sharma RK, Keshari JR, Sinha A. Environmental Exposure: Effect on Maternal Morbidity and Mortality and Neonatal Health. Cureus. 2023;15(5):e38548.
- World Health Organization. Maternal health. https://www.who.int/health-topics/maternal-health#tab=tab_1. Published October 2022. Accessed March 6, 2023.
- Glick I, Kadish E, Rottenstreich M. Management of Pregnancy in Women of Advanced Maternal Age: Improving Outcomes for Mother and Baby. Int J Womens Health. 2021;13:751-759.
- Sweeting A, Wong J, Murphy HR, Ross GP. A Clinical Update on Gestational Diabetes Mellitus. Endocr Rev. 2022;43(5):763-793. doi:10.1210/endrev/bnac003
- Sinkey RG, Battarbee AN, Bello NA, Ives CW, Oparil S, Tita ATN. Prevention, Diagnosis, and Management of Hypertensive Disorders of Pregnancy: a Comparison of International Guidelines. Curr Hypertens Rep. 2020;22(9):66. doi:10.1007/s11906-020-01082-w
- Dayal S, Hong PL. Premature Rupture of Membranes. StatPearls Publishing; 2023 https://www.ncbi.nlm.nih.gov/books/NBK532888/#_article-27659_s2_ Published July 2022. Accessed March 6, 2023.
- Correa-de-Araujo R, Yoon SSS. Clinical Outcomes in High-Risk Pregnancies Due to Advanced Maternal Age. J Womens Health. 2021;30(2):160-167.
- Suzuki S. Clinical significance of pregnancy in adolescence in Japan. J Matern Fetal Neonatal Med. 2019;32(11):1864-1868.
- Kanmaz AG, İnan AH, Beyan E, Ögür S, Budak A. Effect of advanced maternal age on pregnancy outcomes: a single-centre data from a tertiary healthcare hospital. J Obstet Gynaecol. 2019;39(8):1104-1111.
- Althabe F, Moore JL, Gibbons L, et al. Adverse maternal and perinatal outcomes in adolescent pregnancies: The Global Network's Maternal Newborn Health Registry study. Reprod Health. 2015;12 Suppl 2(Suppl 2):S8.
- Suárez-Idueta L, Bedford H, Ohuma EO, Cortina-Borja M. Maternal Risk Factors for Small-for-Gestational-Age Newborns in Mexico: Analysis of a Nationwide Representative Cohort. Front Public Health. 2021;9:707078.
- Kenny LC, Lavender T, McNamee R, O'Neill SM, Mills T, Khashan AS. Advanced maternal age and adverse pregnancy outcome: evidence from a large contemporary cohort. PLoS One. 2013;8(2):e56583.
- Pinheiro RL, Areia AL, Mota Pinto A, Donato H. Advanced Maternal Age: Adverse Outcomes of Pregnancy, A Meta-Analysis. Acta Med Port. 2019;32(3):219-226.
- Tarín JJ, García-Pérez MA, Cano A. Potential risks to offspring of intrauterine exposure to maternal age-related obstetric complications. Reprod Fertil Dev. 2017;29(8):1468-1476.
- Lee WL, Chang WH, Wang PH. Risk factors associated with preterm premature rupture of membranes (PPROM). Taiwan J Obstet Gynecol. 2021;60(5):805-806.
The impact of maternal age distribution on pregnancy-related complications and neonatal outcomes: a single-center retrospective experience
Abstract
Aim: To determine possible risks for mother and baby in advanced age pregnancies.
Materials and Methods: This study is a retrospective archive review examining 14192 cases who gave live births between 24 and 42 weeks between 2020-2023.
Results: The frequency of preeclampsia, gestational hypertension, gestational diabetes mellitus, rupture of membranes and possible miscarriage was high in advanced-age pregnant women compared to other groups. When the groups were compared according to neonatal outcomes, the frequency of low birth weight in adolescence was high than in advanced-age pregnant women. When the groups were compared in terms of macrosomia, the frequency of macrosomia was high in the older age group than in the other groups.
Conclusion: It should be known that pregnancies at an advanced-age can be more complicated for both mother and baby, and pregnancy follow-up should be done more carefully.
Keywords
Advanced age pregnancy Adolescent pregnancy Pregnancy complications Premature rupture of membranes Neonatal outcomes
Ethical Statement
The study received non-interventional ethics committee approval from the Ethics Committee of Van Regional Training and Research Hospital. The approval number is 2023/01-05. The study was managed in accordance with the principles of the Declaration of Helsinki.
Supporting Institution
No person/organization is supporting this study financially.
References
- Osterman M, Hamilton B, Martin JA, Driscoll AK, Valenzuela CP. Births: Final Data for 2020. Natl Vital Stat Rep. 2021;70(17):1-50.
- World Health Organization. United Nations Department of Economic and Social Affairs. World Population Prospects: 2019 Revision. Geneva, Switzerland: World Health Organization; 2019.
- General Directorate of Civil Registration and Nationality. TurkStat, Birth Statistics, 2014.
- Meh C, Thind A, Ryan B, Terry A. Levels and determinants of maternal mortality in northern and southern Nigeria. BMC Pregnancy Childbirth. 2019;19(1):417.
- Kumari U, Sharma RK, Keshari JR, Sinha A. Environmental Exposure: Effect on Maternal Morbidity and Mortality and Neonatal Health. Cureus. 2023;15(5):e38548.
- World Health Organization. Maternal health. https://www.who.int/health-topics/maternal-health#tab=tab_1. Published October 2022. Accessed March 6, 2023.
- Glick I, Kadish E, Rottenstreich M. Management of Pregnancy in Women of Advanced Maternal Age: Improving Outcomes for Mother and Baby. Int J Womens Health. 2021;13:751-759.
- Sweeting A, Wong J, Murphy HR, Ross GP. A Clinical Update on Gestational Diabetes Mellitus. Endocr Rev. 2022;43(5):763-793. doi:10.1210/endrev/bnac003
- Sinkey RG, Battarbee AN, Bello NA, Ives CW, Oparil S, Tita ATN. Prevention, Diagnosis, and Management of Hypertensive Disorders of Pregnancy: a Comparison of International Guidelines. Curr Hypertens Rep. 2020;22(9):66. doi:10.1007/s11906-020-01082-w
- Dayal S, Hong PL. Premature Rupture of Membranes. StatPearls Publishing; 2023 https://www.ncbi.nlm.nih.gov/books/NBK532888/#_article-27659_s2_ Published July 2022. Accessed March 6, 2023.
- Correa-de-Araujo R, Yoon SSS. Clinical Outcomes in High-Risk Pregnancies Due to Advanced Maternal Age. J Womens Health. 2021;30(2):160-167.
- Suzuki S. Clinical significance of pregnancy in adolescence in Japan. J Matern Fetal Neonatal Med. 2019;32(11):1864-1868.
- Kanmaz AG, İnan AH, Beyan E, Ögür S, Budak A. Effect of advanced maternal age on pregnancy outcomes: a single-centre data from a tertiary healthcare hospital. J Obstet Gynaecol. 2019;39(8):1104-1111.
- Althabe F, Moore JL, Gibbons L, et al. Adverse maternal and perinatal outcomes in adolescent pregnancies: The Global Network's Maternal Newborn Health Registry study. Reprod Health. 2015;12 Suppl 2(Suppl 2):S8.
- Suárez-Idueta L, Bedford H, Ohuma EO, Cortina-Borja M. Maternal Risk Factors for Small-for-Gestational-Age Newborns in Mexico: Analysis of a Nationwide Representative Cohort. Front Public Health. 2021;9:707078.
- Kenny LC, Lavender T, McNamee R, O'Neill SM, Mills T, Khashan AS. Advanced maternal age and adverse pregnancy outcome: evidence from a large contemporary cohort. PLoS One. 2013;8(2):e56583.
- Pinheiro RL, Areia AL, Mota Pinto A, Donato H. Advanced Maternal Age: Adverse Outcomes of Pregnancy, A Meta-Analysis. Acta Med Port. 2019;32(3):219-226.
- Tarín JJ, García-Pérez MA, Cano A. Potential risks to offspring of intrauterine exposure to maternal age-related obstetric complications. Reprod Fertil Dev. 2017;29(8):1468-1476.
- Lee WL, Chang WH, Wang PH. Risk factors associated with preterm premature rupture of membranes (PPROM). Taiwan J Obstet Gynecol. 2021;60(5):805-806.
Details
| Primary Language | English |
|---|---|
| Subjects | Obstetrics and Gynaecology |
| Journal Section | Research Article |
| Authors | |
| Publication Date | December 31, 2023 |
| Submission Date | July 15, 2023 |
| Acceptance Date | October 10, 2023 |
| Published in Issue | Year 2023 Volume: 9 Issue: 3 |
