Quality Control Analysis of the Plants Sold as Senna in Turkey

Didem Deliorman Orhan; Esma Sayın

Quality Control Analysis of the Plants Sold as Senna in Turkey

Year 2016, Volume: 6 Issue: 3, 116 - 120, 27.10.2016

Abstract

Objective: The aim of this study was to perform quality control analysis of the plants sold as senna in the market.

Methods: The samples obtained from akhtars were evaluated according to European Pharmacopoeia 7.0 standard. Macroscopic, microscopic, and quantitative microscopy (stomatal index) studies and total ash, loss on drying, ash insoluble in hydrochloric acid, and foreign matter analyses were performed in the samples. Quantitative and qualitative analyses of sennosides in the samples were performed by thin layer chromatography (TLC) and ultraviolet spectroscopy (UV) spectroscopy methods.

Results: According to the results of the analysis, the samples were not found to be suitable as per the officinal drug standards in European Pharmacopoeia 7.0.

Conclusion: According to the results of the quality control analysis, senna samples sold by akhtars were observed to be unsafe for the treatment of constipation.

References

Dünya Sağlık Örgütü. Monographs on Selected Medicinal Plants (Vol. 1). Geneva: WHO; 1999. p. 241-9.
The Plant List [Internet]. Royal Botanic gardens, Kew and Missouri Bota- nical Garden [updated 2013 September; cited 2016 March 17]. Available from: http://www.theplantlist.org/tpl1.1/record/ild-1115.
Erduran Nemutlu F. Çanakkale’de dış mekan süs bitkisi işletmelerinin de- ğerlendirilmesi. Kastamonu Univ J For Fac 2013; 13: 72-83.
Baytop T. Türkiye’de Bitkiler ile Tedavi. 2. Baskı. İstanbul: Nobel Tıp Kita- bevleri; 1999.
Metzger W, Reif K. Determination of 1,8-dihydroxyanthranoids in Senna. J Chromatogr A 1996; 740: 133-8. [CrossRef]
Yılmaz G. Cassia acutifolia-Cassia angustifolia (Sinameki). In: Demirezer Ö, Ersöz T, Saraçoğlu İ, Şener B, editors Tedavide Kullanılan Bitkiler ‘’FFD Monografları’’. 2nd ed. Ankara: Nobel Tıp Kitabevleri; 2011. p. 109-12.
European Pharmacopoeia. 7th ed. Germany: Druckerei C.H. Beck Press; 2011. p. 1236-1238.
Brendel WD, Schneider D. Quantitative determination of sennosides in senna pods and senna leaves. I. Method. Planta Med 1974; 25: 63-7. [CrossRef]
Brendel WD, Schneider D. Quantitative analysis of folia and fructus Sen- nae. II. Planta Med. 1974; 25: 342-9. [CrossRef]

Türkiye’de Sinameki Olarak Satılan Bitkiler Üzerinde Yapılan Kalite Kontrol Analizleri

Year 2016, Volume: 6 Issue: 3, 116 - 120, 27.10.2016

Didem Deliorman Orhan Esma Sayın

Abstract

Amaç: Bu çalışmanın amacı, piyasada “sinameki” olarak satılan bitkilerin kalite kontrollerinin yapılmasıdır.

Yöntemler: Aktarlardan alınan örnekler Avrupa Farmakopesi 7,0 standartlarına göre değerlendirilmiştir. Bu örneklerde makroskobik, mikroskobik ve kantitatif mikroskobi (stoma indisi) çalışmaları, yabancı madde tayini, kurutmada kayıp, bütün kül miktar tayini ve asitte çözünmeyen kül tayini yapılmıştır. Örneklerdeki sennozitlerin kalitatif ve kantitatif analizleri ince tabaka kromatografisi (İTK) ve ultraviyole spektroskobisi (UV) yöntemleri ile yapılmıştır.

Bulgular: Tüm analiz sonuçlarına göre, örneklerin Avrupa Farmakopesi 7,0’da yer alan tıbbi drog standartlarına uygun olmadığı bulunmuştur.

Sonuç: Kalite kontrol analiz sonuçlarına göre, aktarlarda sinameki olarak satılan örneklerin kabızlık tedavisi için çok güvenilir olmadığı gözlenmiştir.

Keywords

Cassia angustifolia, Cassia acutifolia, Sinameki, Avrupa Farmakopesi 7

References

Dünya Sağlık Örgütü. Monographs on Selected Medicinal Plants (Vol. 1). Geneva: WHO; 1999. p. 241-9.
The Plant List [Internet]. Royal Botanic gardens, Kew and Missouri Bota- nical Garden [updated 2013 September; cited 2016 March 17]. Available from: http://www.theplantlist.org/tpl1.1/record/ild-1115.
Erduran Nemutlu F. Çanakkale’de dış mekan süs bitkisi işletmelerinin de- ğerlendirilmesi. Kastamonu Univ J For Fac 2013; 13: 72-83.
Baytop T. Türkiye’de Bitkiler ile Tedavi. 2. Baskı. İstanbul: Nobel Tıp Kita- bevleri; 1999.
Metzger W, Reif K. Determination of 1,8-dihydroxyanthranoids in Senna. J Chromatogr A 1996; 740: 133-8. [CrossRef]
Yılmaz G. Cassia acutifolia-Cassia angustifolia (Sinameki). In: Demirezer Ö, Ersöz T, Saraçoğlu İ, Şener B, editors Tedavide Kullanılan Bitkiler ‘’FFD Monografları’’. 2nd ed. Ankara: Nobel Tıp Kitabevleri; 2011. p. 109-12.
European Pharmacopoeia. 7th ed. Germany: Druckerei C.H. Beck Press; 2011. p. 1236-1238.
Brendel WD, Schneider D. Quantitative determination of sennosides in senna pods and senna leaves. I. Method. Planta Med 1974; 25: 63-7. [CrossRef]
Brendel WD, Schneider D. Quantitative analysis of folia and fructus Sen- nae. II. Planta Med. 1974; 25: 342-9. [CrossRef]

There are 9 citations in total.

Details

Journal Section	Articles
Authors	Didem Deliorman Orhan Esma Sayın This is me
Publication Date	October 27, 2016
Submission Date	September 23, 2016
Published in Issue	Year 2016 Volume: 6 Issue: 3

Cite

APA	Deliorman Orhan, D., & Sayın, E. (2016). Quality Control Analysis of the Plants Sold as Senna in Turkey. Clinical and Experimental Health Sciences, 6(3), 116-120.
AMA	Deliorman Orhan D, Sayın E. Quality Control Analysis of the Plants Sold as Senna in Turkey. Clinical and Experimental Health Sciences. September 2016;6(3):116-120.
Chicago	Deliorman Orhan, Didem, and Esma Sayın. “Quality Control Analysis of the Plants Sold As Senna in Turkey”. Clinical and Experimental Health Sciences 6, no. 3 (September 2016): 116-20.
EndNote	Deliorman Orhan D, Sayın E (September 1, 2016) Quality Control Analysis of the Plants Sold as Senna in Turkey. Clinical and Experimental Health Sciences 6 3 116–120.
IEEE	D. Deliorman Orhan and E. Sayın, “Quality Control Analysis of the Plants Sold as Senna in Turkey”, Clinical and Experimental Health Sciences, vol. 6, no. 3, pp. 116–120, 2016.
ISNAD	Deliorman Orhan, Didem - Sayın, Esma. “Quality Control Analysis of the Plants Sold As Senna in Turkey”. Clinical and Experimental Health Sciences 6/3 (September 2016), 116-120.
JAMA	Deliorman Orhan D, Sayın E. Quality Control Analysis of the Plants Sold as Senna in Turkey. Clinical and Experimental Health Sciences. 2016;6:116–120.
MLA	Deliorman Orhan, Didem and Esma Sayın. “Quality Control Analysis of the Plants Sold As Senna in Turkey”. Clinical and Experimental Health Sciences, vol. 6, no. 3, 2016, pp. 116-20.
Vancouver	Deliorman Orhan D, Sayın E. Quality Control Analysis of the Plants Sold as Senna in Turkey. Clinical and Experimental Health Sciences. 2016;6(3):116-20.